Utilization Alkaline Water as An Alternative Complementary Therapy on Triglyceride Levels among Patients with Grade I Hypertension

Authors

  • Putri Wulandari Poltekkes Kemenkes Semarang
  • Ari Suwondo
  • Rr. Sri Endang Puji Astuti

DOI:

https://doi.org/10.35654/ijnhs.v3i6.358

Keywords:

Keywords : Alkaline Water, Complementary Therapy, Triglyceride Levels, Hypertension.

Abstract

Cardiovascular disease a non-communicable disease with a high incidence in Indonesia. Non-communicable diseases are increasing every year, especially in Indonesia. An alternative treatment for hypertension with complementary therapy is alkaline water, which can improve triglyceride levels. This study aimed to examine alkaline water's effect as an alternative, complementary medicine on triglyceride levels among patients with hypertension grade I. This research quasi-experimental with a design using pre-test-test and post-test control group design. Data collection involved 40 respondents of phase I hypertension patients, selected through non-probability sampling with a purposive sampling method divided into two groups. The intervention group received therapy, captopril drug, and simvastatin, with the consumption of alkaline water 8.5 doses 1.5 liters per day for 21 days. In contrast, the control group was only assigned medication according to the doctor's prescription and mineral water consumption with normal power of hydrogen (pH). Independent t-test results showed significant differences with the average triglyceride levels p-value 0.000 (<0.05). The intervention group is better at lowering triglyceride levels than the control group seen from the higher difference values. Conclusion in utilizing alkaline water with a pH of 8.5 doses 1.5 liters per day for 21 days effectively reduces triglyceride levels in grade I hypertension patients

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References

(1) Anies. Waspada Ancaman Penyakit Tidak Menular: Solusi Pencegahan Aspek Perilaku & Lingkungan. Jakarta: PT. Elex Media Komputindo;; 2006.

(2) World Health Organization. 2015 [cited 2019 Oktober]; Available from: http://www.wma.net/en/20activities/30publichealth/10noncommunicabledisease s/index.html.

(3) Kementrian Kesehatan R. Buletin Jendela Data dan Informasi Kesehatan Penyait Tidak Menular. In: Kesehatan K, editor. Jakarta Pusat Data dan Informasi Kementrian Kesehatan RI;; 2012. p. 1-28.

(4) The Jakarta Post; 2011 [diakses tanggal 29 Oktober 2015].Tersedia dari: http://www.thejakartapost.com/news/2011/06/23/indonesialosesbillionsdiabetes-chronic-diseases.html

(5) World Health Organization W, 2013.Cardiovascular Diseases. [Cited 2016 March 16th].Available from: http://www.who.int/mediacentre/factsheds/fs317/en

(6) GBD 2015 Risk Factors Collaborators. Global r, and national comparative risk assessment of 79 behavioral, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388:1659–1724.

(7) Mills KT BJ, Kelly TN, Reed JE, Kearney PM, Reynolds K, Chen J, Et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016;134:441–450.

(8) US Burden of Disease Collaborators. The state of US health bod, injuries, and risk factors. JAMA. 2013;310:591–608.

(9) Forouzanfar MH LP, Roth GA, Ng M, Biryukov S, Marczak L, Alexander L, Et al. Global burden of hypertension and systolic blood pressure of at least 110 to 115 mm Hg, 1990–2015. JAMA. 2017;317:165–182.

(10) Price SA WL. Patofisiologi konsep klinis proses-proses penyakit. Jakarta: ECG; 2006.

(11) Marliani Lili d. 100 Question & Answers Hipertensi. Jakarta: PT Elex Media Komputindo, Gramedia.; 2007.

(12) Yuliani F. OF, Iryani D. Hubungan Berbagai faktor Risiko Terhadap Kejadian Penyakit Jantung Koroner Pada Penderita Diabetes Melitus Tipe 2. Jurnal Kesehatan Andalas. 2014;3 (1):38-9

(13) American Heart Association. (, 2015). Classification of hyperlipidemias and hyperlipoproteinemia. AHA journals -Running.

(14) Kemenkes R. Riset Kesehatan Dasar ; RISKESDAS. Jakarta Balitbang Kemenkes Ri, 2013.

(15) Setiadi S. Buku ajar ilmu penyakit dalam. Jakarta Interna Publishing; 2009.

(16) Whelton PK CR, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, DePalma SM, et al. 2017. Guideline for the prevention d, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension. 2018;71: e13–e115. DOI: 10.1161/HYP.0000000000000065.

(17) Arfania M, Budiarti RNY. Analisa Kepatuhan Minum Obat Antihipertensi Pada Pasien Dewasa Poli Penyakit Dalam Di Rsud Karawang. Pharma Xplore: Jurnal Sains dan Ilmu Farmasi. 2019;4(1):303-9.

(18) Darnindro N, Sarwono J. Prevalensi Ketidakpatuhan Kunjungan Kontrol pada Pasien Hipertensi yang Berobat di Rumah Sakit Rujukan Primer dan Faktor-Faktor yang Memengaruhi. Jurnal Penyakit Dalam Indonesia. 2017;4(3):123-7.

(19) Sudoyo AW, Alwi I, Simadibrata M, Setiati S. Buku ajar ilmu penyakit dalam jilid ii. Edisi VI. Jakarta:Interna Publishing; 2014.

(20) Whelton (2017), Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

(21) Kemenkes R. Riset Kesehatan Dasar; . Jakarta: Balitbang Kemenkes RI, 2018.

(22) Dinas KPJT. Profil Kesehatan Kabupaten dan Kota di Kawa Tengah 2015. Semarang: Dinas Kesehatan Provinsi Jawa Tengah, 2016.

(23) Durackova Z., 2010. Some Current Insights into Oxidative Stress. Physiological Research. Vol. 59 p-.

(24) Abdel SM YE, & Hafez HF. 2011. The Antioxidant Status of The Plasma in Patients With Breast Cancer Undergoing Chemotherapy. Open Journal of Molecular and Integrative Physiology, vol. 1, pp. 29-35.

(25) Jha JC MB, Adhikari D, Vishwanath P, & Nagamma T. 2014. Cigarette smoke-induced oxidative insult in the local population of Pokhara. Kathmandu University Medical Journal. Vol 5, no. 4, pp. 511-517.

(26) Werdhasari A. Peran antioksidan bagi kesehatan. Jurnal Biotek Medisiana Indonesia. 2014;3(2):59-68.

(27) Longo DL KD, Jameson JL, Fauci AS, Hauser SL, Loscalzo J (eds.) Harrison’s principles of internal medicine. Edisi ke18. New York: Mc Graw Hill; 2011.

(28) Wijayanti S, Wulan ES. Pengaruh Teknik Relaksasi Nafas Dalam Terhadap Penurunan Tekanan Darah Pada Pasien Hipertensi Di Rsud Dr. Loekmono Hadi Kudus. Prosiding HEFA (Health Events for All). 2017;1(1).

(29) Rofacky HF, Aini F. Pengaruh Terapi Spiritual Emotional Freedom Technique (SEFT) terhadap Tekanan Darah Penderita Hipertensi. Jurnal Keperawatan Soedirman. 2015;10(1):41-52.

(30) Johan D. Pengaruh Senam Yoga Terhadap Penurunan Tekanan Darah Pada Lansia yang Mengalami Hipertensi di Wilayah Kerja Puskesmas Air Dingin Padang. 2011.

(31) Herawati KMSN. Pengaruh Senam Yoga Terhadap Penurunan Tekanan Darah Pada Lansia Di Keluran Kampung Jawa Wilayah Kerja Puskesmas Tanjung Paku Kta Solok Tahun 2017. Menara Ilmu. 2018;12(3).

(32) Endang T. Pelayanan Keperawatan Bagi Penderita Hipertensi. Graha Ilmu Yogyakarta: Yogyakarta; 2014

(33) Supriadi D, Hutabarat E, Monica V. Pengaruh Terapi Musik Tradisional Kecapi Suling Sunda Terhadap Tekanan Darah Pada Lansia Dengan Hipertensi. None. 2015;1(2):29-35.

(34) Dalimartha S, dkk. (2008). Care Your Self Hipertensi. Jakarta: Plus.

(35) Hardinsyah. Ilmu Gizi : Teori dan Aplikasi. Jakarta: EGC; 2016.

(36) Pereira Alexander RA VA, Cortez DAG, Szerwieski LLD, Cortez LER. Traditional use of mediclinical plants of eldery. Ref da rede Enferm do Nord. 2016;17 (3):427-34.

(37) Henry MJ, C. PhysicoChemical, Biological and Therapeutic Characteristics of Electrolyzed Reduced Alkaline Water (ERAW). Water. 2013;5(4):2094-115.

(38) Ignacio RMC KH, Yun Y, Easter M, Sajo J V, Yoon Y, et al. 2013. The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC / Nga Mice. Evidence-based Complement Altern Med:1–5.

(39) Nakao AT, Y.; Sharma, P.; Evans, M.; Guthrie, N. Effectiveness of hydrogen-rich water on antioxidant status of subjects with potential metabolic syndrome—An open-label pilot study. J. Clin. Biochem. Nutr. 2010, 46, 140–149. .

(40) Weidman J, Holsworth RE, Brossman B, Cho DJ, Cyr JS, Fridman G. Effect of electrolyzed high-pH alkaline water on healthy adults' blood viscosity. Journal of the International Society of Sports Nutrition. 2016;13(1):45.

(41) Megawati S. Pengaruh Pemberian Air Alkali Terhadap Kadar Kolesterol Total Pada Tikus Putih Jantan Galur Sprague Dawley. Jurnal Farmagazine. 2017;4(2):38-42.

(42) Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, et al. Supplementation of hydrogen-rich water improves lipid and glucose metabolism patients with type 2 diabetes or impaired glucose tolerance. Nutrition Research. 2008;28(3):137-43.

(43) Ignacio RMC, Joo KB, Lee K-J. Clinical effect and mechanism of alkaline reduced water. Journal of Food and Drug Analysis. 2012;20(Suppl 1):394-7.

(44) Patel K, Sant L, Yadav P, Patel D, Sindhi K, Patel S, et al. Alkaline Water: The Disease Fighting Water. 2014.

(45) Lestari DHAK, Kalsium, Magnesium, dan Natrium,Indeks Massa Tubuh, serta Aktifitas Fisik dengan Kejadian Hipertensi pada Wanita Usia 30 – 40 Tahun (Skripsi). Semarang: Universitas Diponegoro; 2010.

(46) Houston M. The importance of potassium in managing hypertension. Curr Hypertens Rep. 2011.

(47) Adesta FEA. Pengaruh Pemberian Simvastatin Terhadap Fungsi Memori Jangka Pendek Tikus Wistar Hiperlipidemi: Faculty of Medicine; 2010.

(48) Hasanah Am. Analisis Interaksi Obat Simvastatin Untuk Penyakit Kolesterol Di Rumah Sakit Umum Haji Medan (Studi Kasus Pada Resep Bulan Januari-Juni 2018): Institut Kesehatan Helvetia Medan; 2018.

(49) Rosita I, Retnosari Andrajati Z. Efek Samping Nyeri Otot dari Simvastatin dan Atorvastatin pada Pasien Jantung RSUD Tarakan. Skripsi Universitas Indonesia. 2014:2-5.

(50) Lajuck P. Ekstrak daun salam (I) lebih efektif menurunkan kadar kolesterol total dan LDL dibandingkan statin pada penderita dislipidemia [tesis]. Denpasar: Universitas Udayana. 2012.

(51) Adib M. Cara mudah memahami dan menghindari hipertensi, jantung, dan stroke. Yogyakarta: Dianloka. 2009.

(52) Murwani S. Profil kadar kolesterol total, low density lipoprotein (LDL) dan gambaran histopatologis aorta pada tikus (Rattus norvegicus) hiperkolesterolemia dengan terapi ekstrak air benalu mangga (Dendropthoe pentandra).[Skripsi]. Malang: Fakultas Kedokteran Hewan Universitas Brawijaya. 2013

Artha C, Mustika A, Sulistyawati SW. Pengaruh Ekstrak Daun Singawalang Terhadap Kadar LDL Tikus Putih Jantan Hiperkolesterolemia. e-Journal Kedokteran Indonesia. 2017;5(2):105-9.

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Published

2020-12-22

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