Risk of cardiovascular disorders in HIV patients in Indonesia: Literature Review

  • Ismail - Fahmi Nurse
Keywords: AIDS, Anti-retroviral therapy, cardiovascular disease, HIV, HIV in Indonesia

Abstract

Abstract

HIV is a major health problem in the world. HIV infection has the effect of reducing immunity status and increasing the risk of cardiovascular disease. Antiretroviral (ART) use as a therapy for HIV also increases the risk of heart disease. Objective: This literature review aims to identify the risk of cardiovascular disorders in HIV patients in Indonesia. Method: literature review of articles published January 2009 to September 2018 using search keywords namely 'Anti-retroviral therapy', 'Cardiovascular disease', 'Corronary artery disease', and 'HIV'. Results: There were 21 journal articles that were relevant to the design and purpose of paper and 3 articles that discussed the risk of heart disease in HIV patients in Indonesia. The results of the literature review showed that HIV patients in Indonesia are at risk of developing cardiovascular disorders which are exacerbated by the use of ART and smoking behavior. The risk of cardiovascular disease includes structural abnormalities and coronary heart disease. Conclusion: HIV patients have a high risk of developing cardiovascular disease. This is a challenge for health workers, the government and researchers, to develop appropriate strategies and methods in reducing the risk of cardiovascular disorders especially in low-middle income country countries such as Indonesia.

Keyword: Anti-retroviral therapy, cardiovascular disease, HIV, AIDS, HIV in Indonesia

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References

1. Bijker R, Choi JY, Ditangco R, Kiertiburanakul S, Lee MP, Law M. Cardiovascular Disease and Cardiovascular Disease Risk in HIV-. 2017;52–66.
2. Boccara F, Lang S, Meuleman C, Ederhy S, Mary-krause M, Costagliola D, et al. HIV and Coronary Heart Disease Time for a Better Understanding. JAC [Internet]. 2013;61(5):511–23. Available from: http://dx.doi.org/10.1016/j.jacc.2012.06.063
3. Hidayat F, Pratiwi D, Kurnia T, Syukri A, Indra P, Amir M, et al. Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids. 2018;4(1):5–10.
4. Kupková P, Heczko M, Kau V, Kryza R. ScienceDirect Review article HIV as a risk factor of coronary artery disease and of acute coronary syndrome : A review and case series. 2017;10–3.
5. Mack M, Gopal A. Epidemiology, Traditional and Novel Risk Factors in Coronary Artery Disease. Heart Fail Clin [Internet]. 2016;12(1):1–10. Available from: http://dx.doi.org/10.1016/j.hfc.2015.08.002
6. Price P. Factors affecting affect cardiovascular health in Indonesian HIV patients beginning. AIDS Res Ther. 2017;1–7.
7. Schwartz T, Magdi G, Steen TW, Sjaastad I. HIV as a risk factor for cardiac disease in Botswana : a cross-sectional study. Int Health [Internet]. 2012;4(1):30–7. Available from: http://dx.doi.org/10.1016/j.inhe.2011.12.003
8. Cerrato E, Calcagno A, Ascenzo FD, Biondi-zoccai G, Mancone M, Marra WG, et al. Cardiovascular disease in HIV patients : from bench to bedside and backwards. 2015;1–10.
9. Ferreira L, Neto P, Rezende F, Feres F, Rocio C, Santos O. Original article Comparison of the ACC / AHA and Framingham algorithms to assess cardiovascular risk in HIV-infected patients. Brazilian J Infect Dis [Internet]. 2017;(x x):4–7. Available from: http://dx.doi.org/10.1016/j.bjid.2017.06.007
10. Vilela AFD, Tura AR de LBR, Hadlich GIFM, Meirelles MV de LBABRLV. Risk of coronary artery disease in individuals infected with human immunodeficiency virus. 2011;521–7.
11. Marbaniang IP, Kadam D, Suman R, Gupte N, Salvi S, Patil S, et al. Cardiovascular risk in an HIV-infected population in India. 2017;1–6.
12. Wang T, Yi R, Ann L, Chelvanambi S, Seimetz M, Clauss M. Increased cardiovascular disease risk in the HIV-positive population on ART : potential role of HIV-Nef and Tat. 2015;24:279–82.
13. Gregson, J., Tang, M., Ndembi, N., Hamers, R. L., Marconi, V. C., Brooks, K., … Murakami-Ogasawara A. Global epidemiology of drug resistance after failure of WHO recommended fi rst-line regimens for adult HIV-1 infection : a multicentre retrospective cohort study. 2016;65(15):1–11.
14. Ek A, Ekblom Ö, Hambraeus K, Cider Å, Kallings L V, Börjesson M. Physical inactivity and smoking after myocardial infarction as predictors for readmission and survival : results from the SWEDEHEART-registry. Clin Res Cardiol. 2018;0(0):0.
15. Muzakkir Amir, H Cipta PK. Relationship Betwen CD4 Count with Troponin I (ctni) level in HIV/AIDS Patients. 2017;22:2017.
16. Pombo M, Olalla J, Del A, La J De, Urdiales D, Aguilar A, et al. European Journal of Internal Medicine Left ventricular hypertrophy detected by echocardiography in HIV-infected patients. Eur J Intern Med [Internet]. 2013;24(6):558–61. Available from: http://dx.doi.org/10.1016/j.ejim.2013.04.007
17. Mansoor A, Golub ET, Dehovitz J, Anastos K, Kaplan RC, Lazar JM. The Association of HIV Infection with Left Ventricular Mass = Hypertrophy. 2009;25(5).
18. Reinsch N, Kahlert P, Esser S, Sundermeyer A, Neuhaus K, Brockmeyer N, et al. Echocardiographic findings and abnormalities in HIV- infected patients : results from a large , prospective , multicenter HIV-heart study. 2011;1(2):176–84.
19. Vachiat A, Mbbc H, Zachariah D, Mbbc H. HIV and Nonischemic Heart Disease. 2017;69(1).
20. Ahmed Vachiat, Keir McCutcheon, Nqoba Tsabedze, Don Zachariah PM. HIV and Ischemic Heart Disease. 2017;69(1).
21. Ballocca F, Ascenzo FD, Gili S, Marra WG, Gaita F. Cardiovascular disease in patients with HIV. Trends Cardiovasc Med [Internet]. 2017;27(8):558–63. Available from: http://dx.doi.org/10.1016/j.tcm.2017.06.005
22. Do TC, Boettiger D, Law M, Pujari S, Zhang F, Chaiwarith R, et al. Smoking and projected cardiovascular risk in an HIV-positive Asian regional cohort. 2016;542–9.
23. Nou E, Lo J, Hadigan C, Grinspoon SK. Pathophysiology and Management of Cardiovascular Disease in HIV-Infected Patients. 2017;4(7):598–610.
24. Ministry of Health of Indonesia year 2017
Published
2019-04-02